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Concussive Injury before or after Controlled Cortical Impact Exacerbates Histopathology and Functional Outcome in a Mixed Traumatic Brain Injury Model in Mice

Traumatic brain injury (TBI) may involve diverse injury mechanisms (e.g., focal impact vs. diffuse impact loading). Putative therapies developed in TBI models featuring a single injury mechanism may fail in clinical trials if the model does not fully replicate multiple injury subtypes, which may occ...

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Bibliographic Details
Main Authors: Dapul, Heda R., Park, Juyeon, Zhang, Jimmy, Lee, Christopher, DanEshmand, Ali, Lok, Josephine, Ayata, Cenk, Gray, Tory, Scalzo, Allison, Qiu, Jianhua, Lo, Eng H., Whalen, Michael J.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593692/
https://ncbi.nlm.nih.gov/pubmed/23153355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2012.2536
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