Cell cycle association and hypoxia regulation of excision repair cross complementation group 1 protein (ERCC1) in tumor cells of head and neck cancer

Excision repair cross complementation group 1 (ERCC1) is a key component of homologous recombination-based repair of interstrand DNA cross-links (ICLs). As a consequence, ERCC1 mediates resistance to mitomycin C (MMC) and platinum chemotherapeutic agents and may predict treatment failure. Clinical r...

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Hauptverfasser: Dudás, József, Schartinger, Volker H., Romani, Angela, Schweigl, Gabriele, Kordsmeyer, Kristian, Marta, Patricia Irina, Url, Christoph, Kral, Florian, Riechelmann, Herbert
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158184/
https://ncbi.nlm.nih.gov/pubmed/24817012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13277-014-2001-2
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