Tumor cell and carcinoma-associated fibroblast interaction regulates matrix metalloproteinases and their inhibitors in oral squamous cell carcinoma

Co-culture of periodontal ligament (PDL) fibroblasts and SCC-25 oral squamous carcinoma cells (OSCC), results in conversion of PDLs into carcinoma-associated fibroblasts (CAFs). Paracrin circuits between CAFs and OSCC cells were hypothesized to regulate the gene expression of matrix remodeling enzym...

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Detalhes bibliográficos
Main Authors: Fullár, Alexandra, Kovalszky, Ilona, Bitsche, Mario, Romani, Angela, Schartinger, Volker Hans, Sprinzl, Georg Mathias, Riechelmann, Herbert, Dudás, József
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378977/
https://ncbi.nlm.nih.gov/pubmed/22516051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2012.03.023
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