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CXCL12-CXCR4 axis promotes the natural selection of breast cancer cell metastasis

CXCR4 and its ligand CXCL12 can promote the proliferation, survival, and invasion of cancer cells. They have been shown to play an important role in regulating metastasis of breast cancer to specific organs. High CXCR4 expression was also correlated to poor clinical outcome. Previous study also show...

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Detalhes bibliográficos
Main Authors: Sun, Yanan, Mao, Xiaoyun, Fan, Chuifeng, Liu, Chong, Guo, Ayao, Guan, Shu, Jin, Quanxiu, Li, Bo, Yao, Fan, Jin, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158177/
https://ncbi.nlm.nih.gov/pubmed/24810923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13277-014-1816-1
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