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A High-Content Assay to Identify Small-Molecule Modulators of a Cancer Stem Cell Population in Luminal Breast Cancer

Breast cancers expressing hormone receptors for estrogen (ER) and progesterone (PR) represent ~70% of all cases and are treated with both ER-targeted and chemotherapies, with near 40% becoming resistant. We have previously described that in some ER(+) tumors, the resistant cells express cytokeratin...

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Autors principals: Yoo, Byong Hoon, Axlund, Sunshine Daddario, Kabos, Peter, Reid, Brian G., Schaack, Jerome, Sartorius, Carol A., LaBarbera, Daniel V.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158006/
https://ncbi.nlm.nih.gov/pubmed/22751729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057112452138
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