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Live Multicellular Tumor Spheroid Models For High-Content Imaging and Screening In Cancer Drug Discovery

The multi cellular tumor spheroid (MCTS) model has been used for decades with proven superiority over monolayer cell culture models at recapitulating in vivo tumor growth. Yet its use in high-throughput drug discovery has been limited, particularly with image based screening, due to practical and te...

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Dettagli Bibliografici
Autori principali: Reid, Brian G., Jerjian, Taleen, Patel, Purvi, Zhou, Qiong, Yoo, Byong Hoon, Kabos, Peter, Sartorius, Carol A., LaBarbera, Daniel V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Bentham Open 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941083/
https://ncbi.nlm.nih.gov/pubmed/24596682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/2213988501408010027
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