Extracellular signal-regulated kinase activation during cardiac hypertrophy reduces sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) transcription

Pathologic cardiac hypertrophy can lead to heart failure, but the mechanisms involved are poorly understood. SERCA2 is critical for normal cardiac calcium handling and function and SERCA2 mRNA and protein levels are reduced by cardiac hypertrophy. We hypothesized that Extracellular Signal-regulated...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Huang, Haiyan, Joseph, Leroy C., Gurin, Michael I., Thorp, Edward B., Morrow, John P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157950/
https://ncbi.nlm.nih.gov/pubmed/25008120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.06.018
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