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A data-driven approach to optimized medication dosing: a focus on heparin

PURPOSE: To demonstrate a novel method that utilizes retrospective data to develop statistically optimal dosing strategies for medications with sensitive therapeutic windows. We illustrate our approach on intravenous unfractionated heparin, a medication which typically considers only patient weight...

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Hlavní autoři: Ghassemi, Mohammad M., Richter, Stefan E., Eche, Ifeoma M., Chen, Tszyi W., Danziger, John, Celi, Leo A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157935/
https://ncbi.nlm.nih.gov/pubmed/25091788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00134-014-3406-5
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