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Cell-Cell Fusion Induced by the Avian Reovirus Membrane Fusion Protein Is Regulated by Protein Degradation

The p10 fusion-associated small transmembrane protein of avian reovirus induces extensive syncytium formation in transfected cells. Here we show that p10-induced cell-cell fusion is restricted by rapid degradation of the majority of newly synthesized p10. The small ectodomain of p10 targets the prot...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shmulevitz, Maya, Corcoran, Jennifer, Salsman, Jayme, Duncan, Roy
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC415793/
https://ncbi.nlm.nih.gov/pubmed/15140997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.11.5996-6004.2004
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