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Palmitoylation, Membrane-Proximal Basic Residues, and Transmembrane Glycine Residues in the Reovirus p10 Protein Are Essential for Syncytium Formation

Avian reovirus and Nelson Bay reovirus are two unusual nonenveloped viruses that induce extensive cell-cell fusion via expression of a small nonstructural protein, termed p10. We investigated the importance of the transmembrane domain, a conserved membrane-proximal dicysteine motif, and an endodomai...

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Detalhes bibliográficos
Main Authors: Shmulevitz, Maya, Salsman, Jayme, Duncan, Roy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC224572/
https://ncbi.nlm.nih.gov/pubmed/12941885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.18.9769-9779.2003
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