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On the perils of poor editing: Regulation of peptide loading by HLA-DQ and H2-A molecules associated with celiac disease and type 1 diabetes
This review discusses mechanisms that link allelic variants of MHC class II molecules (MHCII) to immune pathology. We focus on HLA-DQ (DQ) alleles associated with celiac disease (CD) and type 1 diabetes (T1D) and the role of the murine DQ-like allele, H2-A(g7) (A(g7)), in murine T1D. MHCII molecules...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4157902/ https://ncbi.nlm.nih.gov/pubmed/22805744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/erm.2012.9 |
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