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Caspase-1-Independent Interleukin-1β Is Required for Clearance of Bordetella pertussis Infections and Whole-Cell Vaccine-Mediated Immunity

Whooping cough remains a significant disease worldwide and its re-emergence in highly vaccinated populations has been attributed to a combination of imperfect vaccines and evolution of the pathogen. The focus of this study was to examine the role of IL-1α/β and the inflammasome in generation of the...

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Detalhes bibliográficos
Main Authors: Place, David E., Muse, Sarah J., Kirimanjeswara, Girish S., Harvill, Eric T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157866/
https://ncbi.nlm.nih.gov/pubmed/25198773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107188
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