Interleukin-1 Receptor Signaling Is Required To Overcome the Effects of Pertussis Toxin and for Efficient Infection- or Vaccination-Induced Immunity against Bordetella pertussis

Interleukin-1 receptor-deficient (IL-1R(−/−)) mice are healthy despite being colonized by commensal microbes but are defective in defenses against specific pathogens, suggesting that IL-1R-mediated effects contribute to immune responses against specific pathogenic mechanisms. To better define the ro...

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Autors principals: Zhang, Xuqing, Hester, Sara E., Kennett, Mary J., Karanikas, Alexia T., Bendor, Liron, Place, David E., Harvill, Eric T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2011
Matèries:
Microbial Immunity and Vaccines
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019879/
https://ncbi.nlm.nih.gov/pubmed/20974829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00590-10
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