Functional Short Tandem Repeat Polymorphism of PTPN11 and Susceptibility to Hepatocellular Carcinoma in Chinese Populations

BACKGROUND: PTPN11, which encodes tyrosine phosphatase Shp2, is a critical gene mediating cellular responses to hormones and cytokines. Loss of Shp2 promotes hepatocellular carcinoma (HCC), suggesting that PTPN11 functions as a tumor suppressor in HCC tumorgenesis. The aim of this study was to evalu...

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Autors principals: Zhao, Xiankun, Hu, Shuxiang, Wang, Lu, Zhang, Qing, Zhu, Xiaodan, Zhao, Hua, Wang, Chaoqun, Tao, Ruiyang, Guo, Siping, Wang, Jing, Xu, Jiejie, He, Yan, Gao, Yuzhen
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157842/
https://ncbi.nlm.nih.gov/pubmed/25198338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106841
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