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The impact of short tandem repeat variation on gene expression

Short tandem repeats (STRs) have been implicated in a variety of complex traits in humans. However, genome-wide studies of the effects of STRs on gene expression thus far have had limited power to detect associations and provide insights into putative mechanisms. Here, we leverage whole genome seque...

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Vydáno v:Nat Genet
Hlavní autoři: Fotsing, Stephanie Feupe, Margoliash, Jonathan, Wang, Catherine, Saini, Shubham, Yanicky, Richard, Shleizer-Burko, Sharona, Goren, Alon, Gymrek, Melissa
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917484/
https://ncbi.nlm.nih.gov/pubmed/31676866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-019-0521-9
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