Single-Step Capsular Transformation and Acquisition of Penicillin Resistance in Streptococcus pneumoniae

The capsule (cps) locus of Streptococcus pneumoniae is flanked by the pbp2x and pbp1a genes, coding for penicillin-binding proteins, enzymes involved in cell wall synthesis that are targets for β-lactams. This linkage suggested to us that selection for β-lactam resistance might coselect for capsular...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Trzciński, Krzysztof, Thompson, Claudette M., Lipsitch, Marc
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2004
Assuntos:	Population Genetics and Evolution
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC415782/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15150231/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.186.11.3447-3452.2004
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