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Single-Step Capsular Transformation and Acquisition of Penicillin Resistance in Streptococcus pneumoniae

The capsule (cps) locus of Streptococcus pneumoniae is flanked by the pbp2x and pbp1a genes, coding for penicillin-binding proteins, enzymes involved in cell wall synthesis that are targets for β-lactams. This linkage suggested to us that selection for β-lactam resistance might coselect for capsular...

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Hlavní autoři: Trzciński, Krzysztof, Thompson, Claudette M., Lipsitch, Marc
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC415782/
https://ncbi.nlm.nih.gov/pubmed/15150231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.11.3447-3452.2004
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