Knock Out of S1P3 Receptor Signaling Attenuates Inflammation and Fibrosis in Bleomycin-Induced Lung Injury Mice Model

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite involved in many critical cellular processes, including proliferation, migration, and angiogenesis, through interaction with a family of five G protein–coupled receptors (S1P1–5). Some reports have implicated S1P as an important in...

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Main Authors: Murakami, Ken, Kohno, Masataka, Kadoya, Masatoshi, Nagahara, Hidetake, Fujii, Wataru, Seno, Takahiro, Yamamoto, Aihiro, Oda, Ryo, Fujiwara, Hiroyoshi, Kubo, Toshikazu, Morita, Satoshi, Nakada, Hiroshi, Hla, Timothy, Kawahito, Yutaka
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157792/
https://ncbi.nlm.nih.gov/pubmed/25198418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106792
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