Expression of Autotaxin and Lysophosphatidic Acid Receptors Increases Mammary Tumorigenesis, Invasion, and Metastases

Lysophosphatidic acid (LPA) acts through high affinity G protein-coupled receptors to mediate a plethora of physiological and pathological activities associated with tumorigenesis. LPA receptors and autotaxin (ATX/LysoPLD), the primary enzyme producing LPA, are aberrantly expressed in multiple cance...

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Autores principales: Liu, Shuying, Umezu-Goto, Makiko, Murph, Mandi, Lu, Yiling, Liu, Wenbin, Zhang, Fan, Yu, Shuangxing, Stephens, L. Clifton, Cui, Xiaojiang, Murrow, George, Coombes, Kevin, Muller, William, Hung, Mien-Chie, Perou, Charles M., Lee, Adrian V., Fang, Xianjun, Mills, Gordon B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157573/
https://ncbi.nlm.nih.gov/pubmed/19477432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.03.027
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