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De novo LINE-1 Retrotransposition in HepG2 Cells Preferentially Targets Gene Poor Regions of Chromosome 13
Long interspersed nuclear elements (Line-1 or L1s) account for ~17% of the human genome. While the majority of human L1s are inactive, ~80–100 elements remain retrotransposition competent and mobilize through RNA intermediates to different locations within the genome. De novo insertions of L1s accou...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4157570/ https://ncbi.nlm.nih.gov/pubmed/25043885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2014.07.001 |
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