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The Promise and Failures of Epigenetic Therapies for Cancer Treatment

Genetic mutations and gross structural defects in the DNA sequence permanently alter genetic loci in ways that significantly disrupt gene function. In sharp contrast, genes modified by aberrant epigenetic modifications remain structurally intact and are subject to partial or complete reversal of mod...

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Detalhes bibliográficos
Main Authors: Bojang, Pasano, Ramos, Kenneth S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823804/
https://ncbi.nlm.nih.gov/pubmed/23831234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ctrv.2013.05.009
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