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Clinical potential of novel therapeutic targets in breast cancer: CDK4/6, Src, JAK/STAT, PARP, HDAC, and PI3K/AKT/mTOR pathways

Breast cancers expressing estrogen receptor α, progesterone receptor, or the human epidermal growth factor receptor 2 (HER2) proto-oncogene account for approximately 90% of cases, and treatment with antiestrogens and HER2-targeted agents has resulted in drastically improved survival in many of these...

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Autori principali: Hosford, Sarah R, Miller, Todd W
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157397/
https://ncbi.nlm.nih.gov/pubmed/25206307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S52762
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