cAMP-dependent, long-lasting inhibition of a K+ current in mammalian neurons.

We report the long-term modulation of K+ channels by cAMP in cultured murine colliculi neurons. A short (1-2 s) application of 8-Br-cAMP induced a long-lasting broadening of the action potential, a loss of after-hyperpolarization, and a reduction in spike accommodation. In agreement with these chang...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ansanay, H, Dumuis, A, Sebben, M, Bockaert, J, Fagni, L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41573/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7604046/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.14.6635
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