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cAMP-dependent, long-lasting inhibition of a K+ current in mammalian neurons.

We report the long-term modulation of K+ channels by cAMP in cultured murine colliculi neurons. A short (1-2 s) application of 8-Br-cAMP induced a long-lasting broadening of the action potential, a loss of after-hyperpolarization, and a reduction in spike accommodation. In agreement with these chang...

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Detalhes bibliográficos
Main Authors: Ansanay, H, Dumuis, A, Sebben, M, Bockaert, J, Fagni, L
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC41573/
https://ncbi.nlm.nih.gov/pubmed/7604046
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