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A truncated human NKG2D splice isoform negatively regulates NKG2D-mediated function
NKG2D is a stimulatory receptor expressed by NK cells and a subset of T cells. NKG2D is crucial in diverse aspects of innate and adaptive immune functions. Here, we characterize a novel splice variant of human NKG2D that encodes a truncated receptor lacking the ligand-binding ectodomain. This trunca...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4157112/ https://ncbi.nlm.nih.gov/pubmed/25092887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400920 |
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