Toll-Like Receptor 4 Expression and Cytokine Responses in the Human Urinary Tract Mucosa

Mucosal pathogens trigger a local innate host response by activating epithelial cells. Bacterial adherence and Toll-like receptor 4 (TLR4) signaling have been implicated as key events in this process. This study addressed the molecular basis of the epithelial response to gram-negative infection in t...

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Autori principali: Samuelsson, Patrik, Hang, Long, Wullt, Björn, Irjala, Heikki, Svanborg, Catharina
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC415697/
https://ncbi.nlm.nih.gov/pubmed/15155619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.6.3179-3186.2004
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