A Rapamycin-Releasing Perivascular Polymeric Sheath Produces Highly Effective Inhibition of Intimal Hyperplasia

Intimal hyperplasia produces restenosis (re-narrowing) of the vessel lumen following vascular intervention. Drugs that inhibit intimal hyperplasia have been developed, however there is currently no clinical method of perivascular drug-delivery to prevent restenosis following open surgical procedures...

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Main Authors: Yu, Xaohua, Takayama, Toshio, Goel, Shakti A., Shi, Xudong, Zhou, Yifan, Kent, K. Craig, Murphy, William L., Guo, Lian-Wang
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156896/
https://ncbi.nlm.nih.gov/pubmed/24852098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.05.017
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