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Z-Selective Olefin Metathesis on Peptides: Investigation of Side-Chain Influence, Preorganization, and Guidelines in Substrate Selection

[Image: see text] Olefin metathesis has emerged as a promising strategy for modulating the stability and activity of biologically relevant compounds; however, the ability to control olefin geometry in the product remains a challenge. Recent advances in the design of cyclometalated ruthenium catalyst...

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Autori principali: Mangold, Shane L., O’Leary, Daniel J., Grubbs, Robert H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156862/
https://ncbi.nlm.nih.gov/pubmed/25102124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja507166g
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