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Gene delivery to Her-2+ breast cancer cells using a two-component delivery system to achieve specificity

Current liposomal gene delivery systems predominately utilize cationic lipids, which efficiently bind and deliver DNA plasmid, but also result in nonspecific gene expression in lung and liver tissue. To improve specificity, a two-component delivery strategy employing neutral liposomes was used to ta...

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Bibliographic Details
Main Authors: Kullberg, Max, McCarthy, Ryan, Anchordoquy, Thomas J.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156850/
https://ncbi.nlm.nih.gov/pubmed/24632244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2014.02.013
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