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Gene delivery to Her-2+ breast cancer cells using a two-component delivery system to achieve specificity

Current liposomal gene delivery systems predominately utilize cationic lipids, which efficiently bind and deliver DNA plasmid, but also result in nonspecific gene expression in lung and liver tissue. To improve specificity, a two-component delivery strategy employing neutral liposomes was used to ta...

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Detalhes bibliográficos
Main Authors: Kullberg, Max, McCarthy, Ryan, Anchordoquy, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156850/
https://ncbi.nlm.nih.gov/pubmed/24632244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2014.02.013
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