Recombinant TIMP-1-GPI inhibits growth of fibrosarcoma and enhances tumor sensitivity to doxorubicin

Fibrosarcomas show a high incidence of recurrence and general resistance to apoptosis. Limiting tumor regrowth and increasing their sensitivity to chemotherapy and apoptosis represent key issues in developing more effective treatments of these tumors. Tissue inhibitor of metalloproteinase 1 (TIMP-1)...

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Autori principali: Bao, Q., Niess, H., Djafarzadeh, R., Zhao, Y., Schwarz, B., Angele, M. K., Jauch, K.-W., Nelson, P. J., Bruns, C. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2013
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156787/
https://ncbi.nlm.nih.gov/pubmed/23934106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11523-013-0294-5
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