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Recombinant TIMP-1-GPI inhibits growth of fibrosarcoma and enhances tumor sensitivity to doxorubicin

Fibrosarcomas show a high incidence of recurrence and general resistance to apoptosis. Limiting tumor regrowth and increasing their sensitivity to chemotherapy and apoptosis represent key issues in developing more effective treatments of these tumors. Tissue inhibitor of metalloproteinase 1 (TIMP-1)...

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Detalhes bibliográficos
Main Authors: Bao, Q., Niess, H., Djafarzadeh, R., Zhao, Y., Schwarz, B., Angele, M. K., Jauch, K.-W., Nelson, P. J., Bruns, C. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156787/
https://ncbi.nlm.nih.gov/pubmed/23934106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11523-013-0294-5
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