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UV damage-induced RNA polymerase II stalling stimulates H2B deubiquitylation
Histone H2B monoubiquitylation plays an important role in RNA polymerase II (RNAPII) elongation. Whether this modification responds to RNAPII stalling is not yet known. We report that both yeast and human cells undergo a rapid and significant H2B deubiquitylation after exposure to UV irradiation. Th...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4156752/ https://ncbi.nlm.nih.gov/pubmed/25136098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403901111 |
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