Mesenchymal stem cells exert anti-proliferative effect on lipopolysaccharide-stimulated BV2 microglia by reducing tumour necrosis factor-α levels

BACKGROUND: Progression of neurodegenerative diseases occurs when microglia, upon persistent activation, perpetuate a cycle of damage in the central nervous system. Use of mesenchymal stem cells (MSC) has been suggested as an approach to manage microglia activation based on their immunomodulatory fu...

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Détails bibliographiques
Auteurs principaux: Jose, Shinsmon, Tan, Shi Wei, Ooi, Yin Yin, Ramasamy, Rajesh, Vidyadaran, Sharmili
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156657/
https://ncbi.nlm.nih.gov/pubmed/25182840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0149-8
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