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Lipopolysaccharide Protects Primary B Lymphocytes from Apoptosis by Preventing Mitochondrial Dysfunction and Bax Translocation to Mitochondria

Mature B lymphocytes undergo apoptosis when they are cultured in the absence of survival factors. Gram-negative bacterial lipopolysaccharide (LPS) prevents this spontaneous apoptosis. This study aimed to better define the signaling pathway(s) involved in the antiapoptotic activity of this endotoxin....

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Detalhes bibliográficos
Main Authors: Souvannavong, Vongthip, Lemaire, Christophe, Chaby, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC415660/
https://ncbi.nlm.nih.gov/pubmed/15155628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.6.3260-3266.2004
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