The PPARα - FGF21 hormone axis contributes to metabolic regulation by the hepatic JNK signaling pathway

The cJun NH(2)-terminal kinase (JNK) stress signaling pathway is implicated in the metabolic response to the consumption of a high fat diet, including the development of obesity and insulin resistance. These metabolic adaptations involve altered liver function. Here we demonstrate that hepatic JNK p...

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Bibliografiske detaljer
Main Authors: Vernia, Santiago, Cavanagh-Kyros, Julie, Garcia-Haro, Luisa, Sabio, Guadalupe, Barrett, Tamera, Jung, Dae Young, Kim, Jason K., Xu, Jia, Shulha, Hennady P., Garber, Manuel, Gao, Guangping, Davis, Roger J.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156535/
https://ncbi.nlm.nih.gov/pubmed/25043817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.06.010
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