Role of the hypothalamic–pituitary–thyroid axis in metabolic regulation by JNK1

The cJun N-terminal kinase 1 (JNK1) is implicated in diet-induced obesity. Indeed, germline ablation of the murine Jnk1 gene prevents diet-induced obesity. Here we demonstrate that selective deficiency of JNK1 in the murine nervous system is sufficient to suppress diet-induced obesity. The failure t...

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Detalhes bibliográficos
Main Authors: Sabio, Guadalupe, Cavanagh-Kyros, Julie, Barrett, Tamera, Jung, Dae Young, Ko, Hwi Jin, Ong, Helena, Morel, Caroline, Mora, Alfonso, Reilly, Judith, Kim, Jason K., Davis, Roger J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811827/
https://ncbi.nlm.nih.gov/pubmed/20080940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1878510
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