Frequent Discordance between ERG Gene Rearrangement and ERG Protein Expression in a Rapid Autopsy Cohort of Patients with Lethal, Metastatic, Castration-Resistant Prostate Cancer

BACKGROUND: ERG rearrangements in localized prostate cancer can be detected with high sensitivity and specificity by immunohistochemistry (IHC). However, recent data suggests that ERG IHC may be less sensitive for ERG rearrangements in castration-resistant prostate cancer (CRPC). Thus, we sought to...

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Bibliografiske detaljer
Main Authors: Udager, Aaron M., Shi, Yang, Tomlins, Scott A., Alva, Ajjai, Siddiqui, Javed, Cao, Xuhong, Pienta, Kenneth J., Jiang, Hui, Chinnaiyan, Arul M., Mehra, Rohit
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156519/
https://ncbi.nlm.nih.gov/pubmed/25043157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22836
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