Long intergenic non-coding RNA HOTAIRM1 regulates cell cycle progression during myeloid maturation in NB4 human promyelocytic leukemia cells

HOTAIRM1 is a long intergenic non-coding RNA encoded in the human HOXA gene cluster, with gene expression highly specific for maturing myeloid cells. Knockdown of HOTAIRM1 in the NB4 acute promyelocytic leukemia cell line retarded all-trans retinoid acid (ATRA)-induced granulocytic differentiation,...

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Autori principali: Zhang, Xueqing, Weissman, Sherman M, Newburger, Peter E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2014
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156508/
https://ncbi.nlm.nih.gov/pubmed/24824789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.28828
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