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The binding of TIA-1 to RNA C-rich sequences is driven by its C-terminal RRM domain
T-cell intracellular antigen-1 (TIA-1) is a key DNA/RNA binding protein that regulates translation by sequestering target mRNAs in stress granules (SG) in response to stress conditions. TIA-1 possesses three RNA recognition motifs (RRM) along with a glutamine-rich domain, with the central domains (R...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4156507/ https://ncbi.nlm.nih.gov/pubmed/24824036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.28801 |
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