The RNA-binding protein hnRNPA2 regulates β-catenin protein expression and is overexpressed in prostate cancer

Introduction The RNA-binding protein hnRNPA2 (HNRNPA2B1) is upregulated in cancer, where it controls alternative pre-mRNA splicing of cancer-relevant genes. Cytoplasmic hnRNPA2 is reported in aggressive cancers, but is functionally uncharacterized. We explored the role of hnRNPA2 in prostate cancer...

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Main Authors: Stockley, Jacqueline, Villasevil, M Eugenia M, Nixon, Colin, Ahmad, Imran, Leung, Hing Y, Rajan, Prabhakar
格式: Artigo
語言:Inglês
出版: Landes Bioscience 2014
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Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156506/
https://ncbi.nlm.nih.gov/pubmed/24823909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.28800
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