Role of Vitamin D(3) in Modulation of ΔNp63α Expression during UVB Induced Tumor Formation in SKH-1 Mice

ΔNp63α, a proto-oncogene, is up-regulated in non-melanoma skin cancers and directly regulates the expression of both Vitamin D receptor (VDR) and phosphatase and tensin homologue deleted on chromosome ten (PTEN). Since ΔNp63α has been shown to inhibit cell invasion via regulation of VDR, we wanted t...

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Detalhes bibliográficos
Main Authors: Hill, Natasha T., Gracia-Maldonado, Gabriel H., Leonard, Mary K., Harper, Amanda R., Tober, Kathleen L., Oberyszyn, Tatiana M., Kadakia, Madhavi P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156396/
https://ncbi.nlm.nih.gov/pubmed/25191969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107052
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