Comparative Activities of the Triterpene Saponin Maesabalide III and Liposomal Amphotericin B (AmBisome) against Leishmania donovani in Hamsters

Maesabalide III (MB-III), an oleane triterpene saponin isolated from the Vietnamese plant Maesa balansae, is a new antileishmanial lead compound whose activity against Leishmania donovani (MHOM/ET/67/L82) in groups of five golden hamsters was evaluated after administration of a single subcutaneous d...

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Autors principals: Maes, Louis, Germonprez, Nils, Quirijnen, Ludo, Van Puyvelde, Luc, Cos, Paul, Vanden Berghe, Dirk
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC415622/
https://ncbi.nlm.nih.gov/pubmed/15155199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.6.2056-2060.2004
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