In Vitro and In Vivo Activities of a Triterpenoid Saponin Extract (PX-6518) from the Plant Maesa balansae against Visceral Leishmania Species

The in vitro and in vivo activities of a mixture of six oleane triterpene saponins, recovered from the methanolic extract of the leaves of the Vietnamese plant Maesa balansae (PX-6518), were evaluated against drug-sensitive visceral Leishmania strains. The in vitro 50% inhibitory concentration (IC(5...

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Autors principals: Maes, Louis, Berghe, Dirk Vanden, Germonprez, Nils, Quirijnen, Ludo, Cos, Paul, De Kimpe, Norbert, Van Puyvelde, Luc
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC310194/
https://ncbi.nlm.nih.gov/pubmed/14693530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.1.130-136.2004
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