Structure of Pneumococcal Peptidoglycan Hydrolase LytB Reveals Insights into the Bacterial Cell Wall Remodeling and Pathogenesis

Streptococcus pneumoniae causes a series of devastating infections in humans. Previous studies have shown that the endo-β-N-acetylglucosaminidase LytB is critical for pneumococcal cell division and nasal colonization, but the biochemical mechanism of LytB action remains unknown. Here we report the 1...

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Bibliographische Detailangaben
Hauptverfasser: Bai, Xiao-Hui, Chen, Hui-Jie, Jiang, Yong-Liang, Wen, Zhensong, Huang, Yubin, Cheng, Wang, Li, Qiong, Qi, Lei, Zhang, Jing-Ren, Chen, Yuxing, Zhou, Cong-Zhao
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156040/
https://ncbi.nlm.nih.gov/pubmed/25002590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.579714
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