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Nigrostriatal dynein changes in A53T alpha-synuclein transgenic mice
The accumulation of misfolded a-synuclein is mechanistically linked to neurodegeneration in Parkinson’s disease (PD) and other alpha-synucleinopathies. However, how alpha-synuclein causes neurodegeneration is unresolved. Several studies have supported the involvement of dynein, the major motor for r...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
F1000Research
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4156029/ https://ncbi.nlm.nih.gov/pubmed/25210616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.3507.1 |
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