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Nigrostriatal dynein changes in A53T alpha-synuclein transgenic mice

The accumulation of misfolded a-synuclein is mechanistically linked to neurodegeneration in Parkinson’s disease (PD) and other alpha-synucleinopathies. However, how alpha-synuclein causes neurodegeneration is unresolved. Several studies have supported the involvement of dynein, the major motor for r...

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Hlavní autoři: Liu, Yan, Yuan, Yu-He, Sun, Jian-Dong, Li, Jing, Li, Zhi-Peng, Chen, Nai-Hong
Médium: Artigo
Jazyk:Inglês
Vydáno: F1000Research 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156029/
https://ncbi.nlm.nih.gov/pubmed/25210616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.3507.1
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