Immunopharmacology of CpG Oligodeoxynucleotides and Ribavirin

To investigate their potential mechanisms of action, the nucleoside analogue ribavirin and a TLR9 agonist were compared. The CpG oligodeoxynucleotides (ODN) demonstrated strong TLR9-related Th1-type effects, and ribavirin appeared only to mediate signaling in TLR-transfected cells. CpG ODN represent...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Vollmer, Jörg, Rankin, Robert, Hartmann, Hanna, Jurk, Marion, Samulowitz, Ulrike, Wader, Tanja, Janosch, Andrea, Schetter, Christian, Krieg, Arthur M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2004
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC415599/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15155243/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.6.2314-2317.2004
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