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Development of CpG-oligodeoxynucleotides for effective activation of rabbit TLR9 mediated immune responses.

CpG-oligodeoxynucleotides (CpG-ODN) are potent immune stimuli being developed for use as adjuvants in different species. Toll-like receptor 9 (TLR9) is the cellular receptor for CpG-ODN in mammalian cells. The CpG-ODN with 18-24 deoxynucleotides that are in current use for human and mouse cells, how...

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Detalhes bibliográficos
Principais autores: Tsung-Hsien Chuang, Chao-Yang Lai, Ping-Hui Tseng, Chiun-Jye Yuan, Li-Chung Hsu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2014-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC4182578?pdf=render
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