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Monitoring Caspase-3 Activation with a Multimodality Imaging Sensor in Living Subjects

PURPOSE: Capsase-3 plays an important role in chemotherapy-induced apoptosis in many cancers. Herein, we applied a multimodality reporter vector to monitor caspase-3 activation indirectly in live cells and tumors of living animals undergoing apoptosis. EXPERIMENTAL DESIGN: A fusion protein (MTF) was...

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Detalhes bibliográficos
Main Authors: Ray, Pritha, De, Abhijit, Patel, Manishkumar, Gambhir, Sanjiv Sam
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155946/
https://ncbi.nlm.nih.gov/pubmed/18794090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-5244
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